Sodium channel biophysics, late sodium current and genetic arrhythmic syndromes.

Arrhythmias arise from breakdown of orderly action potential (AP) activation, propagation and recovery driven by interactive opening and closing of successive voltage-gated ion channels, in which one or more Na(+) current components play critical parts. Early peak, Na(+) currents (I Na) reflecting c...

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Autori principali: Chadda, K, Jeevaratnam, K, Lei, M, Huang, C
Natura: Journal article
Lingua:English
Pubblicazione: Springer Verlag 2017

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