The Role of CD4+ T Follicular Helper Cells in HIV Infection: From the Germinal Center to the Periphery.

The Role of CD4+ T Follicular Helper Cells in HIV Infection: From the Germinal Center to the Periphery.

T follicular helper cells (TFh) are key components of the adaptive immune system; they are primarily found in germinal centers (GCs) where their interaction with B cells supports humoral immune responses and efficient antibody production. They are defined by the expression of CXC receptor 5, program...

书目详细资料
Main Authors:	Thornhill, J, Fidler, S, Klenerman, P, Frater, J, Phetsouphanh, C
格式:	Journal article
语言:	English
出版:	Frontiers Media 2017

相似书籍

CD32 expressing doublets in HIV-infected gut-associated lymphoid tissue are associated with a T follicular helper cell phenotype
由: Thornhill, J, et al.
出版: (2019)

Editorial: CD4 T Follicular Helper Cells in HIV
由: Smita S. Iyer
出版: (2017-12-01)

Impact of chronic HIV/SIV infection on T follicular helper cell subsets and germinal center homeostasis
由: Stéphanie Graff-Dubois, et al.
出版: (2016-11-01)

CD4 T cells mediate both positive and negative regulation of the immune response to HIV infection: complex role of T follicular helper cells and Regulatory T cells in pathogenesis
由: Chansavath ePhetsouphanh, et al.
出版: (2015-01-01)

Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers.
由: Wallin, E, et al.
出版: (2014)

Germinal center B cell depletion diminishes CD4+ follicular T helper cells in autoimmune mice.
由: Isharat Yusuf, et al.
出版: (2014-01-01)

IL-7 and CD4 T Follicular Helper Cells in HIV-1 Infection
由: Francesca Chiodi, et al.
出版: (2017-04-01)

Targeting HIV/SIV infection of CD4+ T follicular helper (Tfh) Cells: BCL6 inhibition represses HIV infection CD4+ T cells and reduces germinal center hyperplasia in rhesus macaque
由: Y. Cai, et al.
出版: (2019-07-01)

Enrichment of the HIV reservoir in CD32+CD4 T cells occurs early and is closely associated with immune checkpoint receptor expression
由: Martin, GE, et al.
出版: (2017)

Memory T follicular helper CD4 T cells
由: J. Scott eHale, et al.
出版: (2015-02-01)

Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling.
由: Marita Chakhtoura, et al.
出版: (2021-07-01)

OA1-2 Enrichment of the HIV reservoir in CD32+ CD4 T cells occurs early and is closely associated with immune checkpoint receptor expression
由: G.E. Martin, et al.
出版: (2017-07-01)

SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques
由: Yashavanth Shaan Lakshmanappa, et al.
出版: (2021-01-01)

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation
由: Victoria Ryg-Cornejo, et al.
出版: (2016-01-01)

Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses
由: Beatris Mastelic-Gavillet, et al.
出版: (2019-08-01)

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection
由: Amania A. Sheikh, et al.
出版: (2019-08-01)

Maintenance of Functional CD57+Cytolytic CD4+T Cells in HIV plus Elite Controllers
由: Phetsouphanh, C, et al.
出版: (2019)

CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA
由: Genevieve E. Martin, et al.
出版: (2018-05-01)

Rapid Emergence of T Follicular Helper and Germinal Center B Cells Following Antiretroviral Therapy in Advanced HIV Disease
由: Chun-Shu Wong, et al.
出版: (2021-12-01)

Pulmonary infection with influenza A virus induces site-specific germinal center and T follicular helper cell responses.
由: Alexander W Boyden, et al.
出版: (2012-01-01)

CD32-expressing CD4 T cells are phenotypically diverse and can contain proviral HIV DNA
由: Martin, G, et al.
出版: (2018)

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults
由: Roider, Julia, et al.
出版: (2018)

Continually recruited naïve T cells contribute to the follicular helper and regulatory T cell pools in germinal centers
由: Julia Merkenschlager, et al.
出版: (2023-10-01)

Germinal Center Cells Turning to the Dark Side: Neoplasms of B Cells, Follicular Helper T Cells, and Follicular Dendritic Cells
由: Rosario Munguía-Fuentes, et al.
出版: (2021-01-01)

Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.
由: Brodie Miles, et al.
出版: (2016-10-01)

Maintenance of Functional CD57+ Cytolytic CD4+ T Cells in HIV+ Elite Controllers
由: Chansavath Phetsouphanh, et al.
出版: (2019-08-01)

Advancing the HIV cure agenda: the next 5 years.
由: Thornhill, J, et al.
出版: (2015)

Divergent Expression of CXCR5 and CCR5 on CD4+ T Cells and the Paradoxical Accumulation of T Follicular Helper Cells during HIV Infection
由: John Zaunders, et al.
出版: (2017-05-01)

Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective
由: Malika Aid, et al.
出版: (2018-06-01)

Characterization of T Follicular Helper Cells and T Follicular Regulatory Cells in HIV-Infected and Sero-Negative Individuals
由: Bradley Salvatore, et al.
出版: (2023-01-01)

Role of Circulating T Follicular Helper Cells and Stem-Like Memory CD4+ T Cells in the Pathogenesis of HIV-2 Infection and Disease Progression
由: Sivasankaran Munusamy Ponnan, et al.
出版: (2021-04-01)

PPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation.
由: Hong-Jai Park, et al.
出版: (2014-01-01)

Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells.
由: Young Uk Kim, et al.
出版: (2015-01-01)

CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture
由: Matthew D. Taylor, et al.
出版: (2020-08-01)

The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses
由: Eirini Moysi, et al.
出版: (2018-08-01)

Follicular Helper CD4+ T Cells in Human Neuroautoimmune Diseases and Their Animal Models
由: Xueli Fan, et al.
出版: (2015-01-01)

In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging
由: Kalliopi Ioannidou, et al.
出版: (2021-02-01)

Repertoire sharing between CD4+ T follicular helper cells in peripheral blood and tonsil
由: Brenna, E, et al.
出版: (2019)

CD4+ T follicular helper and IgA+ B cell numbers in gut biopsies from HIV-infected subjects on antiretroviral therapy are comparable to HIV-uninfected individuals
由: John Zaunders, et al.
出版: (2016-10-01)

Follicular Helper CD4+ T Cells, Follicular Regulatory CD4+ T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
由: Xue Zhang, et al.
出版: (2021-01-01)