RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.

Controlled release of promoter-proximal paused RNA polymerase II (RNA Pol II) is crucial for gene regulation. However, studying RNA Pol II pausing is challenging, as pause-release factors are almost all essential. In this study, we identified heterozygous loss-of-function mutations in SUPT5H, which...

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Bibliographic Details
Main Authors:	Martell, DJ, Merens, HE, Caulier, A, Fiorini, C, Ulirsch, JC, Ietswaart, R, Choquet, K, Graziadei, G, Brancaleoni, V, Cappellini, MD, Scott, C, Roberts, N, Proven, M, Roy, NBA, Babbs, C, Higgs, DR, Sankaran, VG, Churchman, LS
Format:	Journal article
Language:	English
Published:	Elsevier 2023

RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation by Martell, DJ, Merens, HE, Fiorini, C, Caulier, A, Ulirsch, JC, Ietswaart, R, Choquet, K, Graziadei, G, Brancaleoni, V, Cappellini, MD, Scott, C, Roberts, N, Proven, M, Roy, NB, Babbs, C, Higgs, DR, Sankaran, VG, Churchman, LS

Published 2023

Internet publication

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.

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