Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

<jats:p>Congenital hypogonadotropic hypogonadism (CHH) is a condition characterized by absent puberty and infertility due to gonadotropin releasing hormone (GnRH) deficiency, which is often associated with anosmia (Kallmann syndrome, KS). We identified loss-of-function heterozygous mutations i...

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Автори: Malone, S, Papadakis, G, Messina, A, Mimouni, N, Trova, S, Imbernon, M, Allet, C, Cimino, I, Acierno, J, Cassatella, D, Xu, C, Quinton, R, Szinnai, G, Pigny, P, Alonso-Cotchico, L, Masgrau, L, Maréchal, J, Prevot, V, Pitteloud, N, Giacobini, P
Формат: Journal article
Мова:English
Опубліковано: eLife Publications 2019

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