Phenotypic dissection of the mouse Ren-1d knockout by complementation with human renin

Phenotypic dissection of the mouse Ren-1d knockout by complementation with human renin

Normal renin synthesis and secretion is important for the maintenance of juxtaglomerular apparatus architecture. Mice lacking a functional Ren-1d gene are devoid of renal juxtaglomerular cell granules and exhibit an altered macula densa morphology. Due to the species-specificity of renin activity, t...

Podrobná bibliografie
Hlavní autoři:	Buckley, C, Nelson, RJ, Mullins, LJ, Sharp, MG, Fleming, S, Kenyon, CJ, Semprini, S, Steppan, D, Peti-Peterdi, J, Kurtz, A, Christian, H, Mullins, JJ
Médium:	Journal article
Jazyk:	English
Vydáno:	American Society for Biochemistry and Molecular Biology 2017

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