Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia

Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia

Progression to aggressive secondary acute myeloid leukaemia (sAML) poses a significant challenge in the management of myeloproliferative neoplasms (MPNs). Since the physiopathology of MPN is closely linked to the activation of interferon (IFN) signalling and that AML initiation and aggressiveness is...

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Bibliographic Details
Main Authors: de Castro, FA, Mehdipour, P, Chakravarthy, A, Ettayebi, I, Loo Yau, H, Medina, TS, Marhon, SA, de Almeida, FC, Bianco, TM, Arruda, AGF, Devlin, R, de Figueiredo‐Pontes, LL, Chahud, F, da Costa Cacemiro, M, Minden, MD, Gupta, V, De Carvalho, DD
Format: Journal article
Language:English
Published: Wiley 2023

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