Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)

The mTOR (mammalian target of rapamycin) signal transduction pathway integrates various signals, regulating ribosome biogenesis and protein synthesis as a function of available energy and amino acids, and assuring an appropriate coupling of cellular proliferation with increases in cell size. In addi...

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Bibliographic Details
Main Authors: Campa, D, Hüsing, A, Stein, A, Dostal, L, Boeing, H, Pischon, T, Tjønneland, A, Roswall, N, Overvad, K, Østergaard, J, Rodríguez, L, Sala, N, Sánchez, M, Larrañaga, N, Huerta, J, Barricarte, A, Khaw, K, Wareham, N, Travis, R, Allen, N, Lagiou, P, Trichopoulou, A, Trichopoulos, D, Palli, D, Sieri, S, Tumino, R, Sacerdote, C, Van Kranen, H, Bueno-De-Mesquita, H, Hallmans, G, Johansson, M, Romieu, I, Jenab, M, Cox, D, Siddiq, A, Riboli, E, Canzian, F, Kaaks, R
Format: Journal article
Language:English
Published: Public Library of Science 2011