The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene.

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene.

DNA sequencing studies indicate that only one of two closely linked human embryonic alpha-like globin genes, zeta (zeta), encodes a functional polypeptide. The other is a pseudogene (psi zeta) that differs by only 3 bp in the protein coding sequence, one of which converts the codon for amino acid 6...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Proudfoot, N, Gil, A, Maniatis, T
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	1982

Antzeko izenburuak

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Argitaratua: (1989)

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GLOBIN GENES AND MESSENGER-RNA FROM HUMANS WITH THALASSEMIA
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Understanding regulation of zeta-globin transcription as the first step towards embryonic globin induction in patients with severe alpha-thalassemia
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Pseudogenes in human cancer
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Protein-Coding Genes in Euarchontoglires with Pseudogene Homologs in Humans
nork: Lev I. Rubanov, et al.
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Intergenic transcription and transinduction of the human beta-globin locus.
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nork: Proudfoot, N
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Globin gene transcripts can utilize histone gene 3' end processing signals.
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Identification of α°-thalassaemia (–SEA) using an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chain detection – a preliminary study
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The PCNA pseudogenes in the human genome
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