Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.

It is recommended that in medial compartment osteoarthritis (OA) unicompartmental knee replacement (UKR) should not be undertaken unless there is bone on bone. This recommendation is not evidence based and it is important to know if it is correct as there are many patients with pain and partial thic...

Full description

Bibliographic Details
Main Authors: Pandit, H, Gulati, A, Jenkins, C, Barker, K, Price, A, Dodd, C, Murray, D
Format: Journal article
Language:English
Published: 2011
_version_ 1826274234472595456
author Pandit, H
Gulati, A
Jenkins, C
Barker, K
Price, A
Dodd, C
Murray, D
author_facet Pandit, H
Gulati, A
Jenkins, C
Barker, K
Price, A
Dodd, C
Murray, D
author_sort Pandit, H
collection OXFORD
description It is recommended that in medial compartment osteoarthritis (OA) unicompartmental knee replacement (UKR) should not be undertaken unless there is bone on bone. This recommendation is not evidence based and it is important to know if it is correct as there are many patients with pain and partial thickness cartilage loss (PTCL) who could potentially benefit from UKR. The aim of this study was to determine if the recommendation is valid. From our database of over 1000 patients treated with the Oxford UKR, we identified 29 with medial OA that had PTCL, confirmed at operation, but otherwise satisfied the recommended indications. This group was matched with 29 knees that had bone exposed (BE) on both sides of the medial compartment and 29 knees that had bone loss (BL) on both sides of the medial compartment. There was no significant difference in the demographics or preoperative scores between the three groups. At a mean follow up of 2 years (range 1-6) the Oxford Knee Score (OKS) of the PTCL group (mean 36 SD 10) was significantly (p < 0.001) worse than the OKS of either the bone exposed group (mean 43 SD 4) or the bone loss group (mean 43 SD 5). 21% of those with PTCL did not benefit substantially from the operation (increase in OKS ≤ 6), whereas all patients in the other groups did. We conclude that the results of UKR for PTCL are unpredictable and therefore that UKR should only be done for medial compartment OA if there is bone on bone. There is a need to develop a method to identify which patients with PTCL will do well so that this subgroup could be treated with UKR.
first_indexed 2024-03-06T22:40:21Z
format Journal article
id oxford-uuid:5b55e98a-476d-4543-bc37-b4bb3d894334
institution University of Oxford
language English
last_indexed 2024-03-06T22:40:21Z
publishDate 2011
record_format dspace
spelling oxford-uuid:5b55e98a-476d-4543-bc37-b4bb3d8943342022-03-26T17:21:32ZUnicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5b55e98a-476d-4543-bc37-b4bb3d894334EnglishSymplectic Elements at Oxford2011Pandit, HGulati, AJenkins, CBarker, KPrice, ADodd, CMurray, DIt is recommended that in medial compartment osteoarthritis (OA) unicompartmental knee replacement (UKR) should not be undertaken unless there is bone on bone. This recommendation is not evidence based and it is important to know if it is correct as there are many patients with pain and partial thickness cartilage loss (PTCL) who could potentially benefit from UKR. The aim of this study was to determine if the recommendation is valid. From our database of over 1000 patients treated with the Oxford UKR, we identified 29 with medial OA that had PTCL, confirmed at operation, but otherwise satisfied the recommended indications. This group was matched with 29 knees that had bone exposed (BE) on both sides of the medial compartment and 29 knees that had bone loss (BL) on both sides of the medial compartment. There was no significant difference in the demographics or preoperative scores between the three groups. At a mean follow up of 2 years (range 1-6) the Oxford Knee Score (OKS) of the PTCL group (mean 36 SD 10) was significantly (p < 0.001) worse than the OKS of either the bone exposed group (mean 43 SD 4) or the bone loss group (mean 43 SD 5). 21% of those with PTCL did not benefit substantially from the operation (increase in OKS ≤ 6), whereas all patients in the other groups did. We conclude that the results of UKR for PTCL are unpredictable and therefore that UKR should only be done for medial compartment OA if there is bone on bone. There is a need to develop a method to identify which patients with PTCL will do well so that this subgroup could be treated with UKR.
spellingShingle Pandit, H
Gulati, A
Jenkins, C
Barker, K
Price, A
Dodd, C
Murray, D
Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title_full Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title_fullStr Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title_full_unstemmed Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title_short Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment.
title_sort unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment
work_keys_str_mv AT pandith unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT gulatia unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT jenkinsc unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT barkerk unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT pricea unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT doddc unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment
AT murrayd unicompartmentalkneereplacementforpatientswithpartialthicknesscartilagelossintheaffectedcompartment