Fine mapping versus replication in whole-genome association studies.

Association replication studies have a poor track record and, even when successful, often claim association with different markers, alleles, and phenotypes than those reported in the primary study. It is unknown whether these outcomes reflect genuine associations or false-positive results. A greater...

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Détails bibliographiques
Auteurs principaux: Clarke, G, Carter, K, Palmer, L, Morris, A, Cardon, L
Format: Journal article
Langue:English
Publié: 2007