Village malaria workers for the community-based management of vivax malaria

In Cambodia, malaria cases are on a trajectory towards the goal of malaria elimination by 2025. Vivax malaria is difficult to eliminate because of hypnozoites that can cause relapse. Primaquine, an 8-aminoquinoline, clears hypnozoites but requires testing for glucose-6-phosphate dehydrogenase (G6PD)...

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Main Authors: Adhikari, B, Tripura, R, Peto, TJ, Callery, JJ, von Seidlein, L, Dysoley, L, Dondorp, AM
Format: Journal article
Language:English
Published: Elsevier 2022
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author Adhikari, B
Tripura, R
Peto, TJ
Callery, JJ
von Seidlein, L
Dysoley, L
Dondorp, AM
author_facet Adhikari, B
Tripura, R
Peto, TJ
Callery, JJ
von Seidlein, L
Dysoley, L
Dondorp, AM
author_sort Adhikari, B
collection OXFORD
description In Cambodia, malaria cases are on a trajectory towards the goal of malaria elimination by 2025. Vivax malaria is difficult to eliminate because of hypnozoites that can cause relapse. Primaquine, an 8-aminoquinoline, clears hypnozoites but requires testing for glucose-6-phosphate dehydrogenase (G6PD) deficiency. Routine primaquine treatment of vivax malaria has recently been implemented in Cambodia in which Village Malaria Workers (VMWs) diagnose vivax malaria by rapid diagnostic test and refer patients to health centres for G6PD testing and further treatment. Patients are referred back to the VMWs for monitoring adverse symptoms and treatment adherence. This article explores how VMWs’ roles might be optimized for the community-based management of vivax malaria. With sufficient training and supervision, the role of VMWs might be expanded to include G6PD testing, making referral to the health centre superfluous. Community-based management of vivax malaria could increase the coverage of radical cure and accelerate vivax malaria elimination.
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spelling oxford-uuid:5b5ca497-a1f5-4a38-b823-45f5abb8b7ff2023-05-30T16:15:27ZVillage malaria workers for the community-based management of vivax malariaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5b5ca497-a1f5-4a38-b823-45f5abb8b7ffEnglishSymplectic ElementsElsevier2022Adhikari, BTripura, RPeto, TJCallery, JJvon Seidlein, LDysoley, LDondorp, AMIn Cambodia, malaria cases are on a trajectory towards the goal of malaria elimination by 2025. Vivax malaria is difficult to eliminate because of hypnozoites that can cause relapse. Primaquine, an 8-aminoquinoline, clears hypnozoites but requires testing for glucose-6-phosphate dehydrogenase (G6PD) deficiency. Routine primaquine treatment of vivax malaria has recently been implemented in Cambodia in which Village Malaria Workers (VMWs) diagnose vivax malaria by rapid diagnostic test and refer patients to health centres for G6PD testing and further treatment. Patients are referred back to the VMWs for monitoring adverse symptoms and treatment adherence. This article explores how VMWs’ roles might be optimized for the community-based management of vivax malaria. With sufficient training and supervision, the role of VMWs might be expanded to include G6PD testing, making referral to the health centre superfluous. Community-based management of vivax malaria could increase the coverage of radical cure and accelerate vivax malaria elimination.
spellingShingle Adhikari, B
Tripura, R
Peto, TJ
Callery, JJ
von Seidlein, L
Dysoley, L
Dondorp, AM
Village malaria workers for the community-based management of vivax malaria
title Village malaria workers for the community-based management of vivax malaria
title_full Village malaria workers for the community-based management of vivax malaria
title_fullStr Village malaria workers for the community-based management of vivax malaria
title_full_unstemmed Village malaria workers for the community-based management of vivax malaria
title_short Village malaria workers for the community-based management of vivax malaria
title_sort village malaria workers for the community based management of vivax malaria
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AT tripurar villagemalariaworkersforthecommunitybasedmanagementofvivaxmalaria
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AT vonseidleinl villagemalariaworkersforthecommunitybasedmanagementofvivaxmalaria
AT dysoleyl villagemalariaworkersforthecommunitybasedmanagementofvivaxmalaria
AT dondorpam villagemalariaworkersforthecommunitybasedmanagementofvivaxmalaria