Does the K-ATP channel participate in the regulation of glucagon secretion?

Does the K-ATP channel participate in the regulation of glucagon secretion?

Manylion Llyfryddiaeth
Prif Awduron:	Bokvist, K, Olsen, H, Hoy, M, Gotfredsen, C, Buschard, K, Rorsman, P, Gromada, J
Fformat:	Journal article
Cyhoeddwyd:	1999

Eitemau Tebyg

G(i2) proteins couple somatostatin receptors to K+-channel activity and exocytosis in glucagon secreting rat A-cells
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Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells.
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Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial-like ATP-sensitive K+ (KATP) conductance in rat pancreatic A-cells.
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Gi2 proteins couple somatostatin receptors to low-conductance K+ channels in rat pancreatic alpha-cells.
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K(ATP)-channels and glucose-regulated glucagon secretion.
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ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
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Does galanin inhibit insulin secretion by opening of the ATP-regulated K+ channel in the beta-cell?
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Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels.
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New insights into the regulation of glucagon secretion by glucagon-like peptide-1.
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Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.
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ATP-REGULATED K+ CHANNELS AND DIABETES-MELLITUS
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Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.
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Evidence from in situ human alpha-cells supporting intrinsic K-ATP channel-dependent regulation of glucagon secretion
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GLUCOSE REGULATION OF GLUCAGON-SECRETION INVOLVES ACTIVATION OF GABAA-RECEPTOR CL--CHANNELS
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Nateglinide, but not repaglinide, stimulates growth hormone release in rat pituitary cells by inhibition of K channels and stimulation of cyclic AMP-dependent exocytosis.
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Nateglinide, but not repaglinide, stimulates growth hormone secretion from rat pituitary cells.
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Somatostatin but not insulin is an important paracrine regulator of glucagon secretion in rat A-cells
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Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.
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Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism.
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Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells.
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Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors.
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Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
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Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.
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Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
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EVIDENCE THAT ADP AND ATP BIND AT DIFFERENT SITES AT THE G-CHANNEL
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GLUCOSE DOES NOT BLOCK ATP-REGULATED K+-CHANNEL ACTIVITY IN FETAL B-CELLS
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Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.
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Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.
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Adrenaline stimulates secretion in rat pancreatic alpha-cells by PKA-dependent acceleration of Ca2+ influx through 1-type Ca2+- channels
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The insulin receptor talks to glucagon?
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