Identification and structure of the nerve growth factor binding site on TrkA.

Identification and structure of the nerve growth factor binding site on TrkA.

Nerve growth factor (NGF) is involved in the development and maintenance of the nervous system and has been implicated as a possible therapeutic target molecule in a number of neurodegenerative diseases, especially Alzheimer's disease. NGF binds with high affinity to the extracellular region of...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Robertson, A, Banfield, M, Allen, S, Dando, J, Mason, G, Tyler, S, Bennett, G, Brain, S, Clarke, A, Naylor, R, Wilcock, G, Brady, R, Dawbarn, D
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2001

Eitemau Tebyg

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Trypanosoma cruzi coaxes cardiac fibroblasts into preventing cardiomyocyte death by activating nerve growth factor receptor TrkA.
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Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling
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