Identification and structure of the nerve growth factor binding site on TrkA.
Nerve growth factor (NGF) is involved in the development and maintenance of the nervous system and has been implicated as a possible therapeutic target molecule in a number of neurodegenerative diseases, especially Alzheimer's disease. NGF binds with high affinity to the extracellular region of...
| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2001
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