Characterisation of tissue homing CD8+ T cells in a murine cytomegalovirus model

Characterisation of tissue homing CD8+ T cells in a murine cytomegalovirus model

<p>Experimental T cell-inducing vaccines seek to generate rapidly responsive, tissue-homing, antigen-specific T cells. CMV induces an unusual memory population (memory "inflation") of highly differentiated effector memory CD8+ T cells specific for a subset of epitopes and as such is...

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Bibliografiske detaljer
Hovedforfatter:	O'Hara, G
Andre forfattere:	Klenerman, P
Format:	Thesis
Sprog:	English
Udgivet:	2013
Fag:	Immunology Infectious diseases

Lignende værker

Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation
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Longitudinal liver sampling in patients with chronic hepatitis B starting antiviral therapy reveals hepatotoxic CD8+ T cells
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Udgivet: (2023-01-01)

ADCC-activating antibodies correlate with decreased risk of congenital human cytomegalovirus transmission
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Udgivet: (2023-07-01)

Characterisation of expression and function of respiratory epithelial CD1d
af: Hajipouran Benam, K
Udgivet: (2014)

Role of the immuno-proteasome in CD8 responses to MCMV
af: Hutchinson, SL
Udgivet: (2009)

Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection
af: Eleanor C. Semmes, et al.
Udgivet: (2022-08-01)

Immunodominant CD8+ T cell responses to HIV-1 infection - 'The good and the bad'
af: Culshaw, A
Udgivet: (2011)

Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines
af: Adele, S
Udgivet: (2024)

Alveolar cells participate in CD8<sup>+</sup> T cell recruitment
af: Lewinsohn David, et al.
Udgivet: (2000-10-01)

A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection
af: Corrah, TW
Udgivet: (2011)

Intranasal immunization with peptide-based immunogenic complex enhances BCG vaccine efficacy in a murine model of tuberculosis
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Udgivet: (2021-02-01)

The role of DOCK8 in the maintenance of CD8+ T cell memory and invariant NKT cells
af: Crawford, G
Udgivet: (2012)

Early IL-10 promotes vasculature-associated CD4+ T cells unable to control Mycobacterium tuberculosis infection
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Udgivet: (2021-11-01)

Function, phenotype and development of human CD161+CD8 T cells
af: Walker, LJ
Udgivet: (2012)

A Leishmania murine model to evaluate the immunomodulatory properties of Pythium insidiosum proteins
af: Tatiana Maria Inêz-Ferreira, et al.
Udgivet: (2017-03-01)

Epidemiology of cytomegalovirus infection in pregnant women living in the Greater Romagna Area, Italy
af: Patrizia Billi, et al.
Udgivet: (2015-12-01)

The role of autophagy in CD8+ T cell immunity
af: Puleston, D, et al.
Udgivet: (2015)

Functional impact of CD161 on T cells
af: Smith, K
Udgivet: (2013)

A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus.
af: Hutchinson, S, et al.
Udgivet: (2011)

Characterisation of the HIV-1 reservoir and the potential for viral eradication
af: Williams, J, et al.
Udgivet: (2014)

Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations
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Udgivet: (2023-04-01)

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells
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Udgivet: (2021-06-01)

High-dimensional mass cytometry identifies T cell and B cell signatures predicting reduced risk of Plasmodium vivax malaria
af: Lisa J. Ioannidis, et al.
Udgivet: (2021-07-01)

Stromal structure remodeling by B lymphocytes limits T cell activation in lymph nodes of Mycobacterium tuberculosis–infected mice
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Udgivet: (2022-11-01)

Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes
af: Bowen Zhang, et al.
Udgivet: (2022-04-01)

Germline IgM predicts T cell immunity to Pneumocystis
af: Kristin Noell, et al.
Udgivet: (2022-09-01)

HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV
af: J Hinkula, et al.
Udgivet: (2017-06-01)

A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion
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Udgivet: (2020)

A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus.
af: Sarah Hutchinson, et al.
Udgivet: (2011-02-01)

Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19
af: Charlotte Thibeault, et al.
Udgivet: (2023-04-01)

Memory T cells possess an innate-like function in local protection from mucosal infection
af: Tanvi Arkatkar, et al.
Udgivet: (2023-05-01)

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
af: Antrobus, R
Udgivet: (2014)

IL-10-producing Th1 cells possess a distinct molecular signature in malaria
af: Chelsea L. Edwards, et al.
Udgivet: (2023-01-01)

Effector Vγ9Vδ2 T cell response to congenital Toxoplasma gondii infection
af: Ling Ma, et al.
Udgivet: (2021-08-01)

Human C. difficile toxin–specific memory B cell repertoires encode poorly neutralizing antibodies
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Udgivet: (2020-08-01)

mTOR regulates T cell exhaustion and PD-1–targeted immunotherapy response during chronic viral infection
af: Satomi Ando, et al.
Udgivet: (2023-01-01)

Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells
af: Hung Le, et al.
Udgivet: (2022-08-01)

NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice
af: Ha-Na Lee, et al.
Udgivet: (2022-02-01)

Characterising novel vaccine adjuvants in eliciting antigen-specific CD8+ T cell immunity
af: He, A
Udgivet: (2023)

Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self
af: Kristina M. Geiger, et al.
Udgivet: (2023-04-01)