Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

A genetically reshaped human IgG1 monoclonal antibody (CAMPATH-1H) was used to treat two patients with non-Hodgkin lymphoma. Doses of 1-20 mg daily were given intravenously for up to 43 days. In both patients lymphoma cells were cleared from the blood and bone marrow and splenomegaly resolved. One p...

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Bibliografiske detaljer
Main Authors:	Hale, G, Dyer, M, Clark, MR, Phillips, J, Marcus, R, Riechmann, L, Winter, G, Waldmann, H
Format:	Journal article
Sprog:	English
Udgivet:	1988

Lignende værker

REMISSION INDUCTION IN PATIENTS WITH LYMPHOID MALIGNANCIES USING UNCONJUGATED CAMPATH-1 MONOCLONAL-ANTIBODIES
af: Dyer, M, et al.
Udgivet: (1990)

Specificity of monoclonal antibody Campath-1.
af: Hale, G, et al.
Udgivet: (1988)

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
af: Hale, G, et al.
Udgivet: (1994)

EFFECTS OF MONOCLONAL-ANTIBODIES OF THE CAMPATH SERIES INVIVO - REQUIREMENTS FOR EFFECTIVE ANTIBODY THERAPY
af: Dyer, M, et al.
Udgivet: (1988)

Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series.
af: Waldmann, H, et al.
Udgivet: (1985)

CAMPATH-1 monoclonal antibody therapy in severe refractory autoimmune thrombocytopenic purpura.
af: Lim, S, et al.
Udgivet: (1993)

RAT MONOCLONAL-ANTIBODIES FOR BONE-MARROW TRANSPLANTATION (BMT) - THE CAMPATH SERIES
af: Waldmann, H, et al.
Udgivet: (1985)

Sustained remission of severe resistant autoimmune neutropenia with Campath-1H.
af: Killick, S, et al.
Udgivet: (1997)

Reshaping human antibodies for therapy.
af: Riechmann, L, et al.
Udgivet: (1988)

The CAMPATH-1 antigen (CDw52).
af: Hale, G, et al.
Udgivet: (1990)

Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H.
af: Isaacs, J, et al.
Udgivet: (1996)

CAMPATH: from concept to clinic.
af: Waldmann, H, et al.
Udgivet: (2005)

Engraftment of marrow allografts treated with Campath-1 monoclonal antibodies.
af: Naparstek, E, et al.
Udgivet: (1999)

Reversal of allograft rejection using the monoclonal antibody, Campath-1G.
af: Friend, P, et al.
Udgivet: (1991)

Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.
af: Williams, R, et al.
Udgivet: (2000)

Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H.
af: Isaacs, J, et al.
Udgivet: (1995)

ISOTYPE VARIANTS OF CAMPATH-1 ANTIBODY - REQUIREMENTS FOR EFFECTIVE ANTIBODY ACTION INVIVO
af: Dyer, M, et al.
Udgivet: (1989)

Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection.
af: Rebello, P, et al.
Udgivet: (1999)

Pilot study of CAMPATH-1, a rat monoclonal antibody that fixes human complement, as an immunosuppressant in organ transplantation.
af: Hale, G, et al.
Udgivet: (1986)

Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype.
af: Dyer, M, et al.
Udgivet: (1989)

Availability of Campath-1 antibodies for bone marrow transplantation.
af: Hale, G, et al.
Udgivet: (1995)

Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H.
af: Newman, D, et al.
Udgivet: (1995)

CAMPATH-1 MOAB IN THE TREATMENT OF REFRACTORY AUTOIMMUNE THROMBOCYTOPENIC PURPURA (ATP)
af: Lim, S, et al.
Udgivet: (1993)

Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation.
af: Hale, G, et al.
Udgivet: (1985)

CAMPATH-1H in inflammatory arthritis.
af: Watts, R, et al.
Udgivet: (1993)

T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation.
af: Hale, G, et al.
Udgivet: (1988)

Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.
af: Hale, G, et al.
Udgivet: (1996)

In vivo 'purging' of residual disease in CLL with Campath-1H.
af: Dyer, M, et al.
Udgivet: (1997)

Leukaemic relapse after Campath 1-treated bone-marrow transplantation for leukaemia.
af: Waldmann, H, et al.
Udgivet: (1987)

ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR LEUKEMIA USING CAMPATH-1 MONOCLONAL-ANTIBODIES AND POSTTRANSPLANT ALLOIMMUNIZATION WITH DONOR LYMPHOCYTES
af: Naparstek, E, et al.
Udgivet: (1993)

CAMPATH-IH in multiple sclerosis.
af: Moreau, T, et al.
Udgivet: (1996)

Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience.
af: Novitzky, N, et al.
Udgivet: (2004)

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
af: Xia, M, et al.
Udgivet: (1993)

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy.
af: Lockwood, C, et al.
Udgivet: (1993)

Evaluation of non-myeloablative conditioning combining beam with in vivo pre-transplant Campath-IG for allogeneic transplantation in patients with lymphoma.
af: Russell, N, et al.
Udgivet: (1999)

CAMPATH-1 antibodies in stem-cell transplantation.
af: Hale, G, et al.
Udgivet: (2001)

Appropriate targets for monoclonal antibodies in the induction of transplantation tolerance.
af: Waldmann, H, et al.
Udgivet: (2001)

TREATMENT OF RHEUMATOID-ARTHRITIS WITH HUMANIZED ANTILYMPHOCYTE ANTIBODY CAMPATH-1H
af: Watts, R, et al.
Udgivet: (1992)

Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?
af: Hale, G, et al.
Udgivet: (2002)

Risks of developing Epstein-Barr virus-related lymphoproliferative disorders after T-cell-depleted marrow transplants. CAMPATH Users.
af: Hale, G, et al.
Udgivet: (1998)