On the origins of diastereoselectivity in the alkylation of diketopiperazine enolates

High levels of diastereoselectivity are observed for benzylation of the lithium enolates of (S)-N,N′-bis-para-methoxybenzyl-3-iso-propyl- piperazine-2,5-dione, (S)-N(1)-para-methoxybenzyl-N(4)-methyl-3-iso-propyl- piperazine-2,5-dione and (S)-N(1)-methyl-N(4)-para-methoxybenzyl-3-iso-propyl- piperaz...

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Bibliografiska uppgifter
Huvudupphovsmän: Bull, S, Davies, S, Garner, A, Parkes, A, Roberts, P, Sellers, T, Smith, A, Tamayo, J, Thomson, J, Vickers, R
Materialtyp: Journal article
Språk:English
Publicerad: 2007