Prime-boost immunisation strategies for tuberculosis.
Vaccines against intracellular pathogens such as Mycobacterium tuberculosis need to induce strong cellular immune responses. Heterologous prime-boost immunisation strategies induce higher levels of both CD4+ and CD8+ T cells than homologous boosting with the same vector. Recombinant pox-viruses are...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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