Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci

Genome-wide association studies (GWAS) have identified >500 common variants associated with quantitative metabolic traits, but in aggregate such variants explain at most 20–30% of the heritable component of population variation in these traits. To further investigate the impact of genotypic v...

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書目詳細資料
Main Authors:	Service, S, Teslovich, T, Fuchsberger, C, Ramensky, V, Yajnik, P, Koboldt, D, Larson, D, Zhang, Q, Lin, L, Welch, R, Ding, L, McLellan, MD, O'Laughlin, M, Fronick, C, Fulton, L, Magrini, V, Swift, A, Elliott, P, Jarvelin, MR, Kaakinen, M, McCarthy, M, Peltonen, L, Pouta, A, Bonnycastle, L, Collins, F, Narisu, N, Stringham, H, Tuomilehto, J, Ripatti, S, Fulton, R, Sabatti, C, Wilson, R, Boehnke, M, Freimer, N
格式:	Journal article
語言:	English
出版:	Public Library of Science 2014

Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci

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