Intragenic transcriptional interference regulates the human immune ligand MICA
Many human genes have tandem promoters driving overlapping transcription, but the value of this distributed promoter configuration is generally unclear. Here we show that MICA, a gene encoding a ligand for the activating immune receptor NKG2D, contains a conserved upstream promoter that expresses a...
| Main Authors: | , , |
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| Format: | Journal article |
| Published: |
EMBO Press
2018
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