Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution.

Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution.

Unlike related biphenyl compounds, 2-arylpyridines and 1-arylisoquinolines can be induced to adopt preferentially one of two axial conformations by the presence of a sulfinyl substituent adjacent to the Ar-Ar bond. In the case of more substituted biaryls, the compounds are atropisomeric, and thermod...

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Bibliografische gegevens
Hoofdauteurs:	Clayden, J, Fletcher, S, McDouall, J, Rowbottom, S
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2009

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