Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: An aromatic hydrocarbon-binding P450 enzyme

CYP108D1 from Novosphingobium aromaticivorans DSM12444 binds a range of aromatic hydrocarbons such as phenanthrene, biphenyl and phenylcyclohexane. Its structure, which is reported here at 2.2 Å resolution, is closely related to that of CYP108A1 (P450terp), an -terpineol-oxidizing enzyme. The compos...

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Hlavní autoři: Bell, S, Yang, W, Yorke, J, Zhou, W, Wang, H, Harmer, J, Copley, R, Zhang, A, Zhou, R, Bartlam, M, Rao, Z, Wong, L
Médium: Journal article
Jazyk:English
Vydáno: 2012