Lack of toxicity and persistence in the mouse associated with administration of candidate DNA- and modified vaccinia virus Ankara (MVA)-based HIV vaccines for Kenya.

Toxicity, biodistribution and persistence of candidate HIV vaccines pTHr.HIVA, a recombinant DNA, and MVA.HIVA, a recombinant modified vaccinia virus Ankara, were determined in the Balb/c mouse. The mice were injected with either two doses of intramuscular pTHr.HIVA DNA (50 microg each, separated by...

Full description

Bibliographic Details
Main Authors: Hanke, T, Mcmichael, A, Samuel, R, Powell, L, McLoughlin, L, Crome, S, Edlin, A
Format: Journal article
Language:English
Published: 2002