Caffeine modulates Ca2+ receptor activation in isolated rat osteoclasts and induces intracellular Ca2+ release.

A ryanodine-sensitive pathway is involved in intracellular Ca2+ release in response to activation of the osteoclast cell surface Ca2+ receptor. We now report that the ryanodine-receptor modulator, caffeine itself released intracellularly stored Ca2+ and, strongly inhibited Ca2+ release triggered in...

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Bibliografske podrobnosti
Main Authors: Shankar, V, Pazianas, M, Huang, C, Simon, B, Adebanjo, O, Zaidi, M
Format: Journal article
Jezik:English
Izdano: 1995