N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models

Ectopic calcification (EC), which is the pathological deposition of calcium and phosphate in extra-skeletal tissues, may be associated with hypercalcaemic and hyperphosphataemic disorders, or it may occur in the absence of metabolic abnormalities. In addition, EC may be inherited as part of several...

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Chi tiết về thư mục
Những tác giả chính:	Esapa, C, Hannan, F, Babinsky, V, Potter, P, Thomas, G, Croucher, P, Brown, M, Brown, S, Cox, R, Thakker, R
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Public Library of Science 2015

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