Selection for resistance to a fungal pathogen in Drosophila melanogaster.
An artificial selection experiment designed to explore the evolution of resistance to a fungal pathogen, Beauveria bassiana, in Drosophila melanogaster is reported here. The experiment was designed to test whether there is sufficient additive genetic variation in this trait for increased resistance...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1826274500023418880 |
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| author | Kraaijeveld, A Godfray, H |
| author_facet | Kraaijeveld, A Godfray, H |
| author_sort | Kraaijeveld, A |
| collection | OXFORD |
| description | An artificial selection experiment designed to explore the evolution of resistance to a fungal pathogen, Beauveria bassiana, in Drosophila melanogaster is reported here. The experiment was designed to test whether there is sufficient additive genetic variation in this trait for increased resistance to evolve, and, if so, whether there are correlated responses that might represent a cost to defence. After 15 generations of selection, flies from selected lines did not have higher overall fitness after infection compared with control lines. The response to selection for resistance against this pathogen is thus much weaker than against other species, in particular, parasitoids. There was, however, evidence for increased late-life fecundity in selected lines, which may indicate evolved tolerance of fungal infection. This increase was accompanied by reduced early-life fitness, which may reflect the well-known trade-off between early and late reproduction. In the absence of fungal infection, selected flies had lower fitness than control flies, and the possibility that this is also a trade-off with increased tolerance is explored. |
| first_indexed | 2024-03-06T22:44:22Z |
| format | Journal article |
| id | oxford-uuid:5ca657b3-b74d-4275-b2fd-338e00d8cc7e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:44:22Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:5ca657b3-b74d-4275-b2fd-338e00d8cc7e2022-03-26T17:29:31ZSelection for resistance to a fungal pathogen in Drosophila melanogaster.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5ca657b3-b74d-4275-b2fd-338e00d8cc7eEnglishSymplectic Elements at Oxford2008Kraaijeveld, AGodfray, HAn artificial selection experiment designed to explore the evolution of resistance to a fungal pathogen, Beauveria bassiana, in Drosophila melanogaster is reported here. The experiment was designed to test whether there is sufficient additive genetic variation in this trait for increased resistance to evolve, and, if so, whether there are correlated responses that might represent a cost to defence. After 15 generations of selection, flies from selected lines did not have higher overall fitness after infection compared with control lines. The response to selection for resistance against this pathogen is thus much weaker than against other species, in particular, parasitoids. There was, however, evidence for increased late-life fecundity in selected lines, which may indicate evolved tolerance of fungal infection. This increase was accompanied by reduced early-life fitness, which may reflect the well-known trade-off between early and late reproduction. In the absence of fungal infection, selected flies had lower fitness than control flies, and the possibility that this is also a trade-off with increased tolerance is explored. |
| spellingShingle | Kraaijeveld, A Godfray, H Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title | Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title_full | Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title_fullStr | Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title_full_unstemmed | Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title_short | Selection for resistance to a fungal pathogen in Drosophila melanogaster. |
| title_sort | selection for resistance to a fungal pathogen in drosophila melanogaster |
| work_keys_str_mv | AT kraaijevelda selectionforresistancetoafungalpathogenindrosophilamelanogaster AT godfrayh selectionforresistancetoafungalpathogenindrosophilamelanogaster |