De novo formation of several features of a centromere following introduction of a Y alphoid YAC into mammalian cells.
The DNA sequence requirements for mammalian centromere function have been investigated by re-introducing human YAC clones containing either centromeric or non-centromeric sequences into hamster and human cells. All YACs integrated into the host chromosomes. In most cell lines produced by spheroplast...
Huvudupphovsmän: | Larin, Z, Fricker, M, Tyler-Smith, C |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1994
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Liknande verk
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