Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5

There is an urgent need for improved malaria vaccine immunogens. Invasion of erythrocytes by Plasmodium falciparum is essential for its life cycle, preceding symptoms of disease and parasite transmission. Antibodies which target PfRH5 are highly effective at preventing erythrocyte invasion and the m...

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Bibliographic Details
Main Authors: Harrison, TE, Alam, N, Farrell, B, Quinkert, D, Lias, AM, King, LDW, Barfod, LK, Draper, SJ, Campeotto, I, Higgins, MK
Format: Journal article
Language:English
Published: Springer 2024

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