Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5
There is an urgent need for improved malaria vaccine immunogens. Invasion of erythrocytes by Plasmodium falciparum is essential for its life cycle, preceding symptoms of disease and parasite transmission. Antibodies which target PfRH5 are highly effective at preventing erythrocyte invasion and the m...
Main Authors: | Harrison, TE, Alam, N, Farrell, B, Quinkert, D, Lias, AM, King, LDW, Barfod, LK, Draper, SJ, Campeotto, I, Higgins, MK |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Springer
2024
|
Similar Items
-
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
by: Weiss, GE, et al.
Published: (2023) -
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites.
by: Greta E Weiss, et al.
Published: (2023-09-01) -
Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria
by: Partey, F, et al.
Published: (2018) -
Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.
by: Douglas, A, et al.
Published: (2014) -
Targeting PfRh5 on Merozoites to Prevent Basigin Binding
by: Papadopoulos Konstantinos
Published: (2012-10-01)