Causal inference in the multisensory brain
When combining information across different senses humans need to flexibly select cues of a common origin whilst avoiding distraction from irrelevant inputs. The brain could solve this challenge using a hierarchical principle, by deriving rapidly a fused sensory estimate for computational expediency...
| Main Authors: | , , , , |
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| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
Elsevier
2019
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| _version_ | 1826274516093894656 |
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| author | Cao, Y Summerfield, C Park, H Giordano, B Kayser, C |
| author_facet | Cao, Y Summerfield, C Park, H Giordano, B Kayser, C |
| author_sort | Cao, Y |
| collection | OXFORD |
| description | When combining information across different senses humans need to flexibly select cues of a common origin whilst avoiding distraction from irrelevant inputs. The brain could solve this challenge using a hierarchical principle, by deriving rapidly a fused sensory estimate for computational expediency and, later and if required, filtering out irrelevant signals based on the inferred sensory cause(s). Analysing time- and source- resolved human magnetoencephalographic data we unveil a systematic spatio- temporal cascade of the relevant computations, starting with early segregated unisensory representations, continuing with sensory fusion in parietal-temporal regions and culminating as causal inference in the frontal lobe. Our results reconcile previous computational accounts of multisensory perception by showing that prefrontal cortex guides flexible integrative behaviour based on candidate representations established in sensory and association cortices, thereby framing multisensory integration in the generalised context of adaptive behaviour. |
| first_indexed | 2024-03-06T22:44:37Z |
| format | Journal article |
| id | oxford-uuid:5cbd3fad-6069-4ab5-bee5-930f072f03a9 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:44:37Z |
| publishDate | 2019 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:5cbd3fad-6069-4ab5-bee5-930f072f03a92022-03-26T17:30:00ZCausal inference in the multisensory brainJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5cbd3fad-6069-4ab5-bee5-930f072f03a9EnglishSymplectic Elements at OxfordElsevier2019Cao, YSummerfield, CPark, HGiordano, BKayser, CWhen combining information across different senses humans need to flexibly select cues of a common origin whilst avoiding distraction from irrelevant inputs. The brain could solve this challenge using a hierarchical principle, by deriving rapidly a fused sensory estimate for computational expediency and, later and if required, filtering out irrelevant signals based on the inferred sensory cause(s). Analysing time- and source- resolved human magnetoencephalographic data we unveil a systematic spatio- temporal cascade of the relevant computations, starting with early segregated unisensory representations, continuing with sensory fusion in parietal-temporal regions and culminating as causal inference in the frontal lobe. Our results reconcile previous computational accounts of multisensory perception by showing that prefrontal cortex guides flexible integrative behaviour based on candidate representations established in sensory and association cortices, thereby framing multisensory integration in the generalised context of adaptive behaviour. |
| spellingShingle | Cao, Y Summerfield, C Park, H Giordano, B Kayser, C Causal inference in the multisensory brain |
| title | Causal inference in the multisensory brain |
| title_full | Causal inference in the multisensory brain |
| title_fullStr | Causal inference in the multisensory brain |
| title_full_unstemmed | Causal inference in the multisensory brain |
| title_short | Causal inference in the multisensory brain |
| title_sort | causal inference in the multisensory brain |
| work_keys_str_mv | AT caoy causalinferenceinthemultisensorybrain AT summerfieldc causalinferenceinthemultisensorybrain AT parkh causalinferenceinthemultisensorybrain AT giordanob causalinferenceinthemultisensorybrain AT kayserc causalinferenceinthemultisensorybrain |