A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.

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Statins are prescribed widely to lower plasma low-density lipoprotein (LDL) concentrations and cardiovascular disease risk and have been shown to have beneficial effects in a broad range of patients. However, statins are associated with an increased risk, albeit small, of clinical myopathy and type...

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Hlavní autoři: Mangravite, L, Engelhardt, B, Medina, M, Smith, J, Brown, C, Chasman, D, Mecham, B, Howie, B, Shim, H, Naidoo, D, Feng, Q, Rieder, M, Chen, Y, Rotter, J, Ridker, P, Hopewell, J, Parish, S, Armitage, J, Collins, R, Wilke, R, Nickerson, D, Stephens, M, Krauss, R
Médium: Journal article
Jazyk:English
Vydáno: 2013

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