Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability
Mutations within BRCA1 predispose carriers to a high risk of breast and ovarian cancers. BRCA1 functions to maintain genomic stability through the assembly of multiple protein complexes involved in DNA repair, cell-cycle arrest, and transcriptional regulation. Here, we report the identification of a...
Main Authors: | Savage, K, Gorski, J, Barros, E, Irwin, G, Manti, L, Powell, A, Pellagatti, A, Lukashchuk, N, McCance, D, McCluggage, W, Schettino, G, Salto-Tellez, M, Boultwood, J, Richard, D, McDade, S, Harkin, D |
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Format: | Journal article |
Udgivet: |
2014
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Lignende værker
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Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability.
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