Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Mutations within BRCA1 predispose carriers to a high risk of breast and ovarian cancers. BRCA1 functions to maintain genomic stability through the assembly of multiple protein complexes involved in DNA repair, cell-cycle arrest, and transcriptional regulation. Here, we report the identification of a...

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Huvudupphovsmän:	Savage, K, Gorski, J, Barros, E, Irwin, G, Manti, L, Powell, A, Pellagatti, A, Lukashchuk, N, McCance, D, McCluggage, W, Schettino, G, Salto-Tellez, M, Boultwood, J, Richard, D, McDade, S, Harkin, D
Materialtyp:	Journal article
Publicerad:	2014

Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability. av Savage, K, Gorski, J, Barros, E, Irwin, G, Manti, L, Powell, A, Pellagatti, A, Lukashchuk, N, McCance, D, McCluggage, W, Schettino, G, Salto-Tellez, M, Boultwood, J, Richard, D, McDade, S, Harkin, D

Publicerad 2014

Journal article

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

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