A flexible and accurate genotype imputation method for the next generation of genome-wide association studies.

Genotype imputation methods are now being widely used in the analysis of genome-wide association studies. Most imputation analyses to date have used the HapMap as a reference dataset, but new reference panels (such as controls genotyped on multiple SNP chips and densely typed samples from the 1,000...

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Autors principals: Howie, B, Donnelly, P, Marchini, J
Format: Journal article
Idioma:English
Publicat: 2009