Neuronal non-CG methylation is an essential target for MeCP2 function

Neuronal non-CG methylation is an essential target for MeCP2 function

DNA methylation is implicated in neuronal biology via the protein MeCP2, the mutation of which causes Rett syndrome. MeCP2 recruits the NCOR1/2 co-repressor complexes to methylated cytosine in the CG dinucleotide, but also to sites of non-CG methylation, which are abundant in neurons. To test the bi...

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Main Authors: Tillotson, R, Cholewa-Waclaw, J, Chhatbar, K, Connelly, JC, Kirschner, SA, Webb, S, Koerner, MV, Selfridge, J, Kelly, DA, De Sousa, D, Brown, K, Lyst, MJ, Kriaucionis, S, Bird, A
格式: Journal article
语言:English
出版: Cell Press 2021

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