The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2alpha but not HIF-1alpha.

BACKGROUND: Regulatory T cells (T(R)) mediate peripheral immunological tolerance and are implicated in tumor progression. Because prostate cancer is being investigated for treatment by immunotherapy, we have assessed tumor T(R) in prostate cancers. METHODS: T(R) cells were identified by FOXP3 in ti...

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Hlavní autoři: Fox, S, Launchbury, R, Bates, G, Han, C, Shaida, N, Malone, P, Harris, A, Banham, A
Médium: Journal article
Jazyk:English
Vydáno: 2007