Childhood cancer incidence in a cohort of twin babies.

We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39-120). Pooled analysis...

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Bibliographic Details
Main Authors: Murphy, M, Whiteman, D, Hey, K, Griffith, M, Gill, L, Goldacre, M, Vincent, T, Bunch, K
Format: Journal article
Language:English
Published: 2001
Description
Summary:We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39-120). Pooled analysis with data from published cohort studies indicates a similar significant incidence reduction (SIR 81, 95% CI 67-96). Further studies are warranted.