IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models

IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models

Recognition of Influenza A virus (IAV) by the innate immune system triggers pathways that restrict viral replication, activates innate immune cells, and regulates adaptive immunity. However, excessive innate immune activation can exaggerate disease. The pathways promoting excessive activation are in...

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Bibliographic Details
Main Authors:	Forbester, JL, Clement, M, Wellington, D, Yeung, A, Dimonte, S, Marsden, M, Chapman, L, Coomber, EL, Tolley, C, Lees, E, Hale, C, Clare, S, Udalova, I, Dong, T, Dougan, G, Humphreys, IR
Format:	Journal article
Language:	English
Published:	American Society for Microbiology 2020

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