Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

The LIM domain protein Lmo2 and the basic helix-loop-helix transcription factor Scl/Tal1 are expressed in early haematopoietic and endothelial progenitors and interact with each other in haematopoietic cells. While loss-of-function studies have shown that Lmo2 and Scl/Tal1 are essential for haematop...

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Detalles Bibliográficos
Autores principales: Gering, M, Yamada, Y, Rabbitts, T, Patient, R
Formato: Journal article
Lenguaje:English
Publicado: 2003

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