Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.

UNLABELLED: Due to its ability to inhibit prometastatic matrix metalloproteinases, tissue inhibitor of metalloproteinases (TIMP)-1 has been thought to suppress tumor metastasis. However, elevated systemic levels of TIMP-1 correlate with poor prognosis in cancer patients, suggesting a metastasis-stim...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Seubert, B, Grünwald, B, Kobuch, J, Cui, H, Schelter, F, Schaten, S, Siveke, J, Lim, N, Nagase, H, Simonavicius, N, Heikenwalder, M, Reinheckel, T, Sleeman, J, Janssen, K, Knolle, P, Krüger, A
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2015