CLONIDINE INHIBITION OF GLUCOSE-STIMULATED INSULIN-RELEASE INVOLVES REDUCTION OF THE CA-2+ CURRENT

Eitemau Tebyg

• Inhibition of glucose-stimulated insulin release by alpha 2-adrenoceptor activation is parallelled by both a repolarization and a reduction in cytoplasmic free Ca2+ concentration.
  gan: Nilsson, T, et al.
  Cyhoeddwyd: (1988)
• Suppression of insulin release by galanin and somatostatin is mediated by a G-protein. An effect involving repolarization and reduction in cytoplasmic free Ca2+ concentration.
  gan: Nilsson, T, et al.
  Cyhoeddwyd: (1989)
• Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.
  gan: Arkhammar, P, et al.
  Cyhoeddwyd: (1990)
• MEMBRANE-POTENTIAL, TRANSMEMBRANE CA-45 FLUXES, CYTOPLASMIC FREE CA-2+ CONCENTRATION ([CA-2+]I) AND INSULIN RELEASE BY TRANSPLANTABLE RAT INSULINOMA CELLS
  gan: Flatt, P, et al.
  Cyhoeddwyd: (1988)
• Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.
  gan: Arkhammar, P, et al.
  Cyhoeddwyd: (1987)