Prolyl hydroxylases and therapeutics.
Prolyl hydroxylases are members of the iron- and 2-oxoglutarate-dependent dioxygenase enzyme family. Collagen prolyl hydroxylase is well known for its involvement in scurvy, in which ascorbate deficiency inhibits the enzyme and results in characteristic signs of the disease. Several distinct prolyl...
Main Authors: | Smith, T, Talbot, N |
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Format: | Journal article |
Language: | English |
Published: |
2010
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