The influence of bioreactor geometry and the mechanical environment on engineered tissues.

A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. The cell population (and attendant extracellular matrix), culture medium, and porous scaffold are treated as distinct phases. The bioreactor system is represented by a two-dimensional channel containi...

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Hlavní autoři: Osborne, J, O'Dea, R, Whiteley, J, Byrne, H, Waters, S
Médium: Journal article
Jazyk:English
Vydáno: 2010