Human rabies and its prevention: an overview.
Human rabies is underreported, but it clearly is still a frequent medical problem that is virtually confined to tropical countries. Rabies encephalitis remains essentially incurable, and most patients die at home, their terrible symptoms unpalliated by sedatives or analgesics. Recent attempts to cur...
| Main Authors: | , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
1988
|
| _version_ | 1826274664942403584 |
|---|---|
| author | Warrell, D Warrell, M |
| author_facet | Warrell, D Warrell, M |
| author_sort | Warrell, D |
| collection | OXFORD |
| description | Human rabies is underreported, but it clearly is still a frequent medical problem that is virtually confined to tropical countries. Rabies encephalitis remains essentially incurable, and most patients die at home, their terrible symptoms unpalliated by sedatives or analgesics. Recent attempts to cure rabies in well-equipped intensive care units have failed, a situation reemphasizing the importance of preventive measures. The great advances that have been made in understanding the rabies virus and the associated improvements in rabies vaccines have had little or no impact in the tropical endemic zone. Most patients who have been exposed to rabies are still given nervous tissue vaccines for postexposure prophylaxis. An urgent priority is the development of a regimen using tissue culture vaccine that is sufficiently economical to replace nervous tissue vaccine. This has been achieved in China with primary hamster kidney cell vaccine. |
| first_indexed | 2024-03-06T22:46:54Z |
| format | Journal article |
| id | oxford-uuid:5d7eb158-f3b2-404f-9036-4219d85cafa8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:46:54Z |
| publishDate | 1988 |
| record_format | dspace |
| spelling | oxford-uuid:5d7eb158-f3b2-404f-9036-4219d85cafa82022-03-26T17:34:46ZHuman rabies and its prevention: an overview.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5d7eb158-f3b2-404f-9036-4219d85cafa8EnglishSymplectic Elements at Oxford1988Warrell, DWarrell, MHuman rabies is underreported, but it clearly is still a frequent medical problem that is virtually confined to tropical countries. Rabies encephalitis remains essentially incurable, and most patients die at home, their terrible symptoms unpalliated by sedatives or analgesics. Recent attempts to cure rabies in well-equipped intensive care units have failed, a situation reemphasizing the importance of preventive measures. The great advances that have been made in understanding the rabies virus and the associated improvements in rabies vaccines have had little or no impact in the tropical endemic zone. Most patients who have been exposed to rabies are still given nervous tissue vaccines for postexposure prophylaxis. An urgent priority is the development of a regimen using tissue culture vaccine that is sufficiently economical to replace nervous tissue vaccine. This has been achieved in China with primary hamster kidney cell vaccine. |
| spellingShingle | Warrell, D Warrell, M Human rabies and its prevention: an overview. |
| title | Human rabies and its prevention: an overview. |
| title_full | Human rabies and its prevention: an overview. |
| title_fullStr | Human rabies and its prevention: an overview. |
| title_full_unstemmed | Human rabies and its prevention: an overview. |
| title_short | Human rabies and its prevention: an overview. |
| title_sort | human rabies and its prevention an overview |
| work_keys_str_mv | AT warrelld humanrabiesanditspreventionanoverview AT warrellm humanrabiesanditspreventionanoverview |