Structural aspects of agonism and antagonism in the oestrogen receptor.

We have determined the three-dimensional structures of both alpha- and beta-forms of the ligand-binding domain of the oestrogen receptor (ER) in complexes with a range of receptor agonists and antagonists. Here, we summarize how these structures provide both an understanding of the ER's distinc...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Pike, A, Brzozowski, A, Walton, J, Hubbard, R, Bonn, T, Gustafsson, J, Carlquist, M
التنسيق: Journal article
اللغة:English
منشور في: 2000