Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses.

Once transcribed, the nascent full-length RNA of HIV-1 must travel to the appropriate host cell sites to be translated or to find a partner RNA for copackaging to form newly generated viruses. In this report, we sought to delineate the location where HIV-1 RNA initiates dimerization and the influenc...

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Detalhes bibliográficos
Main Authors: Moore, M, Nikolaitchik, O, Chen, J, Hammarskjöld, M, Rekosh, D, Hu, W
Formato: Journal article
Idioma:English
Publicado em: Public Library of Science 2009