Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes.

The ability to define and manipulate the interaction of peptides with MHC molecules has immense immunological utility, with applications in epitope identification, vaccine design, and immunomodulation. However, the methods currently available for prediction of peptide-MHC binding are far from ideal....

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Bibliographic Details
Main Authors: Doytchinova, I, Walshe, V, Jones, N, Gloster, SE, Borrow, P, Flower, DR
Format: Journal article
Language:English
Published: 2004

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