Biophysical characterisation of fibulin-5 proteins associated with disease.

Biophysical characterisation of fibulin-5 proteins associated with disease.

FBLN5 encodes fibulin-5, an extracellular matrix calcium-binding glycoprotein that is essential for elastic fibre formation. FBLN5 mutations are associated with two distinct human diseases, age-related macular degeneration (AMD) and cutis laxa (CL), but the biochemical basis for the pathogenic effec...

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Bibliographic Details
Main Authors:	Schneider, R, Jensen, SA, Whiteman, P, McCullagh, J, Redfield, C, Handford, P
Format:	Journal article
Language:	English
Published:	2010

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