An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates
The efficient synthesis of an octameric furanose carbopeptoid, readily purified by chromatography in ethyl acetate:hexane (2:1), is reported. Extensive NMR studies suggest that two tetrameric 5- aminomethyltetrahydrofuran-2-carboxylates are prone to adopt solution conformations reminiscent of a repe...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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| _version_ | 1797071061923135488 |
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| author | Claridge, T Long, D Hungerford, N Aplin, RT Smith, M Marquess, D Fleet, G |
| author_facet | Claridge, T Long, D Hungerford, N Aplin, RT Smith, M Marquess, D Fleet, G |
| author_sort | Claridge, T |
| collection | OXFORD |
| description | The efficient synthesis of an octameric furanose carbopeptoid, readily purified by chromatography in ethyl acetate:hexane (2:1), is reported. Extensive NMR studies suggest that two tetrameric 5- aminomethyltetrahydrofuran-2-carboxylates are prone to adopt solution conformations reminiscent of a repeating β-turn, a third tetramer and the corresponding octamer may tend towards a left-handed α-helix. |
| first_indexed | 2024-03-06T22:47:48Z |
| format | Journal article |
| id | oxford-uuid:5dc84266-599a-4402-9e20-273662283076 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:47:48Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:5dc84266-599a-4402-9e20-2736622830762022-03-26T17:36:32ZAn octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylatesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5dc84266-599a-4402-9e20-273662283076EnglishSymplectic Elements at Oxford1999Claridge, TLong, DHungerford, NAplin, RTSmith, MMarquess, DFleet, GThe efficient synthesis of an octameric furanose carbopeptoid, readily purified by chromatography in ethyl acetate:hexane (2:1), is reported. Extensive NMR studies suggest that two tetrameric 5- aminomethyltetrahydrofuran-2-carboxylates are prone to adopt solution conformations reminiscent of a repeating β-turn, a third tetramer and the corresponding octamer may tend towards a left-handed α-helix. |
| spellingShingle | Claridge, T Long, D Hungerford, N Aplin, RT Smith, M Marquess, D Fleet, G An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title | An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title_full | An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title_fullStr | An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title_full_unstemmed | An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title_short | An octameric carbopeptoid; Secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates |
| title_sort | octameric carbopeptoid secondary structure in octameric and tetrameric 5 aminomethyl tetrahydrofuran 2 carboxylates |
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