Studies on HIF hydroxylases

<p>Hypoxia-inducible factor (HIF) is the master regulator of genes involved in adaptation to hypoxia. The stability and transcriptional activity of HIF are regulated by post-translational hydroxylations: prolyl hydroxylation by the prolyl hydroxylase domain-containing enzymes PHD1 – 3 earmarks...

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Dades bibliogràfiques
Autor principal: Webb, J
Altres autors: Pugh, C
Format: Thesis
Idioma:English
Publicat: 2008
Matèries: