Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery.
Eighty patients with rheumatoid arthritis who had 129 surgical procedures on the hand and wrist over a 5-year period were reviewed. All patients continued with their usual medication throughout the perioperative period. There were 2 pin track infections and 1 wound infection in patients taking metho...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2002
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| _version_ | 1797071088187867136 |
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| author | Jain, A Witbreuk, M Ball, C Nanchahal, J |
| author_facet | Jain, A Witbreuk, M Ball, C Nanchahal, J |
| author_sort | Jain, A |
| collection | OXFORD |
| description | Eighty patients with rheumatoid arthritis who had 129 surgical procedures on the hand and wrist over a 5-year period were reviewed. All patients continued with their usual medication throughout the perioperative period. There were 2 pin track infections and 1 wound infection in patients taking methotrexate alone (3 of 48), 1 wound dehiscence in a patient taking steroids without methotrexate (1 of 30), 1 wound infection in a patient taking both drugs (1 of 30), and 2 wound infections in patients taking neither of these drugs (2 of 21). There was no statistically significant risk of wound infection or breakdown in patients taking methotrexate or steroids or both. Rheumatoid patients with diabetes had an increased risk of wound infection (33%) compared with patients without (3.3%). No disease flare-ups occurred within 3 months of surgery. We recommend that these drugs be continued throughout the surgical and postoperative rehabilitation period. |
| first_indexed | 2024-03-06T22:48:11Z |
| format | Journal article |
| id | oxford-uuid:5dea7dda-73d3-4cd8-a0fe-0d1a2160ef3b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:48:11Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:5dea7dda-73d3-4cd8-a0fe-0d1a2160ef3b2022-03-26T17:37:14ZInfluence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5dea7dda-73d3-4cd8-a0fe-0d1a2160ef3bEnglishSymplectic Elements at Oxford2002Jain, AWitbreuk, MBall, CNanchahal, JEighty patients with rheumatoid arthritis who had 129 surgical procedures on the hand and wrist over a 5-year period were reviewed. All patients continued with their usual medication throughout the perioperative period. There were 2 pin track infections and 1 wound infection in patients taking methotrexate alone (3 of 48), 1 wound dehiscence in a patient taking steroids without methotrexate (1 of 30), 1 wound infection in a patient taking both drugs (1 of 30), and 2 wound infections in patients taking neither of these drugs (2 of 21). There was no statistically significant risk of wound infection or breakdown in patients taking methotrexate or steroids or both. Rheumatoid patients with diabetes had an increased risk of wound infection (33%) compared with patients without (3.3%). No disease flare-ups occurred within 3 months of surgery. We recommend that these drugs be continued throughout the surgical and postoperative rehabilitation period. |
| spellingShingle | Jain, A Witbreuk, M Ball, C Nanchahal, J Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title | Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title_full | Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title_fullStr | Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title_full_unstemmed | Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title_short | Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery. |
| title_sort | influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery |
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